职称 副教授

学位 博士

政治面貌 中共党员

邮箱 tuxiao@mail.hzau.edu.cn

研究方向 水产动物病害防控 

教育经历

2014年9月-2019年6月在西北农林科技大学动物科技学院学习，获博士学位

2010年9月-2014年7月在西北农林科技大学动物科技学院学习，获学士学位

主要职历

2022年6月至今，yl6809永利官网，副教授，硕士生导师

2019年7月-2022年5月，华南师范大学生命科学学院，博士后

科研成果

主要研究内容：

主要从事水产动物寄生虫病防控研究，围绕鱼类重大寄生虫病流行病学、致病机制、无公害渔药研发开展研究工作。形成了以下三个研究方向：

1. 挖掘天然小分子抗虫新靶标并阐明抗虫机制；

2. 抗虫先导化合物的构效关系及结构优化；

3. 构建水产动物寄生虫病生态和药物防控体系。

主要奖励情况：

1. 入选中国科协第八届青年人才托举工程计划

2. 获2022年陕西省自然科学二等奖（第四完成人）

主持和参与的科研项目：

1. 中国科协第八届（2022-2024）青年人才托举工程项目（2022QNRC001），30万元，2022.11-2024.10，主持

2. 国家自然科学基金面上项目（3237210291），50万元，2024.01-2027.12，主持

3. 国家自然科学基金青年项目（32002403），24万元，2021.01-2023.12，主持

4. 广东省自然科学基金面上项目（2022A1515011033），10万元，2022.01-2024.12，主持

5. 中国博士后科学基金面上项目（2019M662958），8万元，2019.11-2022.04，主持

6. 中央高校基本科研业务费专项基金-科研启动经费（510322228），2022.09-2025.08，20万元，主持

7. 国家自然科学基金面上项目（31772873），60万元，2018.01-2021.12，参与

8. 国家特色淡水鱼产业技术体系岗位科学家（CARS-46-21），2021-2025，350万，参与

发表的科研论文：

1. Tu Xiao, Tan Xiaoping, Qi Xiaozhou, Huang Aiguo, Ling Fei*, Wang Gaoxue*. Proteome interrogation using gold nanoprobes to identify targets of arctigenin in fish parasites. J. Nanobiotechnol., 2020, 18: 32.

2. Tu Xiao*, Duan Chenxi, Wu Siwei, Fu Shengli, Ye Jianmin*. Identification of plumbagin as an effective chemotherapeutic agent for treatment of Gyrodactylus infections. Aquaculture. 2021, 535: 736372

3. Tu Xiao, Qi Xiaozhou, Huang Aaiguo, Ling Fei*, Wang Gaoxue*. Cytokine gene expression profiles in goldfilsh (Carassius auratus) during Gyrodactylus kobayashii infection. Fish Shellfish Immunol. 2019, 86: 116-124.

4. Li Jiadong, Lian Zirun, Wu Zhelin, Zeng Lihua, Mu Liangliang, Yuan Ye, Bai Hao, Guo Zheng, Mai Kangsen, Tu Xiao*, Ye Jianmin*. Artificial intelligence–based method for the rapid detection of fish parasites (Ichthyophthirius multifiliis, Gyrodactylus kobayashii, and Argulus japonicus). Aquaculture. 2023, 563:738790.

5. Hu Jingbo, Yang Hao, Tu Xiao*, Gu Zemao*. Epicatechin gallate: A promising agent isolated from Sargentodoxa cuneate for the treatment of ichthyophthiriasis in goldfish (Carassius auratus). Aquaculture. 2023, 574:739724.

6. Zhang Yilin, Tan Xiaoping, Tu Xiao*, Ling Fei, Wang Gaoxue*. Efficacy and antiparasitic mechanism of curdione from Curcuma zedoaria against Gyrodactylus kobayashii in goldfish. Aquaculture. 2020, 523.

7. Ye Jianmin*, Li Lan, Duan Chenxi, Wu Liting, Tu Xiao*, Vogelbein Mary Ann, Bromage Erin*, Kaattari Stephen L. IgM-bearing B cell affinity subpopulations possess differential antigen sensitivity in rainbow trout. Fish Shellfish Immunol. 2021, 118: 111-118.

8. Duan Chenxi, Ma Zhihao, Wu Siwei, Ding Xuejuan, Tu Xiao*, Ye Jianmin*. Functional characterization of complement factor D on the defense against Gyrodactylus kobayashii (Monogenea) infection in goldfish (Carassius auratus). Aquaculture. 2021, 543:737214

9. Tu Xiao, Huang Aiguo, Hu Yang, Ling Fei*, Wang Gaoxue*. Arctigenin: An emerging candidate against infections of Gyrodactylus. Aquaculture. 2018, 495: 983-991.

10. Tu Xiao, Liu Lei, Qi Xiaozhou, Chen Weichao, Wang Gaoxue*, Ling Fei*. Characterization of Toll-like receptor gene expression in goldfish (Carassius auratus) during Dactylogyrus intermedius infection. Dev. Comp. Immunol. 2016, 63: 78-83.

11. Tu Xiao, Ling Fei, Huang Aiguo, Wang Gaoxue*. The first report of Dactylogyrus formosus Kulwiec, 1927 (Monogenea: Dactylogyridae) from goldfish (Carassius auratus) in central China. Parasitol. Res. 2015a, 114: 2689-2696.

12. Tu Xiao, Ling Fei*, Huang Aiguo, Wang Gaoxue*. An infection of Gyrodactylus kobayashii Hukuda, 1940 (Monogenea) associated with the mortality of goldfish (Carassius auratus) from central China. Parasitol. Res. 2015b, 114: 737-745.

13. Tu Xiao, Ling Fei, Huang Aiguo, Zhang Qizhong*, Wang Gaoxue*. Anthelmintic efficacy of Santalum album (Santalaceae) against monogenean infections in goldfish. Parasitol. Res. 2013, 112: 2839-2845.

14. Kong Linghe, Qian Kun, Wu Siwei, Li Bingxi, Guo Zhen, Yin Xiaoxue, Huang Yu, Ye Jianmin, Tu Xiao*, Fu Shengli*. Functional characterization of TNF-alpha in pufferfish (Takifugu obscurus) in immune response and apoptosis against Aeromonas hydrophila. J. Fish Dis. 2021, 44: 1343-1353.

15. Wu Siwei, Duan Chenxi, Kong Linghe, Tu Xiao*, Wang Lifei, Guo Zhen*, Ye Jianmin*. Interleukin-10 (IL-10) participates in host defense against bacterial pathogens and promotes IgM antibody production in Nile tilapia (Oreochromis niloticus). Aquaculture. 2021, 531.

16. Zhou Enxu, Yan Fangfang, Li Bingxi, Chen Meng, Tu Xiao*, Wu Siwei, Wu Hairong, Wei Xiufang, Fu Shengli, Wu Liting, Guo Zhen, Ye Jianmin*. Molecular and functional characterization of IL-6 receptor (IL-6R) and glycoprotein 130 (gp130) in Nile tilapia (Oreochromis niloticus). Dev. Comp. Immunol., 2020, 106: 103629

17. Ling Fei^#, Tu Xiao^#, Huang Aiguo, Wang Gaoxue*. Morphometric and molecular characterization of Dactylogyrus vastator and D. intermedius in goldfish (Carassius auratus). Parasitol. Res. 2016, 115: 1755-1765.

18. Hu Yang, Shen Yufeng, Wu Xiaohu, Tu Xiao, Wang Gaoxue*. Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents. Eur. J. Med. Chem. 2018, 143: 958-969.

授权和申请专利：

1. 发明专利. 顾泽茂，胡静波，涂笑，杨浩. 表儿茶素没食子酸酯在制备防治鱼类小瓜虫病药物中的应用CN202310270335.4

2. 发明专利. 顾泽茂，徐智威，胡瑞雪，涂笑，李丹，胡鉴轩. 一种稻鸭虾一体化绿色养殖田ZL202223012582.4

备注

欢迎对鱼类寄生虫学、新药研发及寄生虫病防控等研究感兴趣的同学加盟。